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I would recommend letting your vet get urine via cystocentesis (with a needle through the abdomen into the bladder). Anything else is not sterile enough to do a urine culture, although a U/A can work.

Bottom line, lots of reasons to cause polyuria, if accompanied by polydypsia (increased water drinking) ranging from basic UTI that can be treated with antibiotics, to severe problems (but unlikely) like renal failure, kidney/bladder stones, diabetes mellitus, thyroid problems, or even Cushings.

:wave: Good luck!
 
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