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A good way to start off would be to have a vet take a look at them, scope them, run a couple slides for mites if the debris looks suspicious, yeast, and bacteria. They can do an initial deep cleaning, and show you how to properly clean your dogs ears with solution that is appropriate for the problem (not all ear cleaners are equal, some are ototoxic, some are drying agents, etc...), and also prescribe any kind of antibiotic/antifungal for your dogs ears.

Most vets will use a non ototoxic drying agent or emulsifier like Oticalm or Cerumene to break up the debris followed by a warm saline flush if necessary. Depending on what they find on an ear cytology they might prescribe a wide range of medications for the specific findings and severity. Always ask to be shown how to properly clean the ears, directions on the bottles, and directions given on the internet won't be as good as an old fashioned hands-on demonstration by a trained professional.

Ear infections are very common in all dogs, so let your vet help you out and point you in the right direction. We can all offer our methods of cleaning, etc...but I don't think anyone can really tell you what to do since we don't know the nature of the ear infection, the state of your dogs inner ear anatomy, or the type of debris you're dealing with.
 
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