8 weeks is the perfect age. I would not wait to have her vaccinated because she is away from her mother and not nursing and is not getting those antibodies anymore :wink:
o, the question is this: Should puppies recieve a smaller dose of vaccine because they are smaller and have less body mass or should puppies recieve a higher vaccine dose because they have circulating maternal antibodies that need to be overcome in order for a proper immune response to be initiated?
Well, for some diseases we do know that puppies should recieve basically more vaccine ie the vaccines that they get should contain more antigen (virus or virus particles which stimulate immunity) so that there is still excess antigen left after the maternal antibodies have neutralized some of it. These vaccines should also be more like the actual infective virus than is necessary for adult dogs. One disease that we use vaccines for puppies in such a manner is canine parvovirus. These types of vaccines are sometimes referred to as "low passage, high titer" vaccines.
For other diseases it seems intuitive that puppies should recieve less vaccine because of their smaller size since we give less dose of drugs to puppies in many cases. Actually, vaccines do not work in the same way as antibiotics or pain-killers do therefore, we should not just assume that puppies need less vaccine. This strategy, then, would not only be applicable to younger dogs, but also to smaller breed dogs as well. Manufactureres of monovalent vaccines (vaccines that immunize against one virus) and polyvalent vaccines (vaccines which immunize against more than one virus) recommend using the same vaccine dose for animals of all ages and sizes such that the average sized animal would recieve a sufficient amout of antigen. Does this mean that toy-breeds are always being overvaccinated and giant breeds are alway being undervaccinated? Is this dependent on whether you are using killed or modified live vaccines? The answer to both of these questions varies according to who you talk to. The "real" answers to these questions lie in future research. For example, we need to be able to understand if bigger animals have a proportionately larger amount of cells in their body that can respond to vaccines and if smaller animals have proportionately fewer cells that can respond. And if there is such a difference, is it clinically significant and should we be dosing more or less based upon it? Some references state that killed vaccines do require dose adjustments based upon body mass, but even this fact isn't really understood yet.
don't you worry about diseases???? especially parvo!?chihuahua-lady said:jacob had his at 8 weeks but i wish i had waited a little longer he was so tiny and if you think about it the vets seem to give the same dose to every sized dog always wondered about that !? im waiting til britney and paris are about 12 weeks
I would like to know to :?luv4mygirls said:don't you worry about diseases???? especially parvo!?chihuahua-lady said:jacob had his at 8 weeks but i wish i had waited a little longer he was so tiny and if you think about it the vets seem to give the same dose to every sized dog always wondered about that !? im waiting til britney and paris are about 12 weeks