The American Animal Hospital Association (AAHA) considers leptospirosis vaccine a “non-core” vaccine for dogs. That is, they do not recommend pets receive it unless there is a good chance they will be exposed to leptospirosis. The main reason for this is that veterinarians see more vaccination reactions following the administration of vaccines containing leptospirosis than any other vaccines. These reactions range from the minor inconveniences of pain at injection site, facial swelling and hives to a fatal anaphylactic reaction. Which pet will experience them cannot be predicted. The immunity that leptospirosis vaccinations give is short lasting – perhaps a year, perhaps less in some dogs. Occasionally, the vaccine does not protect at all... So you and your veterinarian must decide if your pet’s risk of catching leptospirosis justifies yearly vaccination. In making that decision you must ask if your pet frequents areas that may harbor leptospirosis. You must also know if leptospirosis is occurring frequently in your community. You must also consider if your pet, or its siblings, have had previous vaccination reactions. Reactions also seem to occur more frequently in smaller breeds than larger ones.