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What Is Addison's Disease In Dogs?
Addison's disease, also known as hypoadrenocorticism, is a condition that causes dogs' adrenal glands to generate insufficient hormones. These hormones are required to regulate a dog's metabolism, blood pressure, and stress reaction. This 4animal article will explain what Addison's disease is, as well as its causes, symptoms, and treatment.

What Causes Addison's Disease In Dogs?

Addison's disease in dogs is caused by damage to the adrenal glands. The adrenal glands are two small glands located near the kidneys that produce several hormones, including cortisol, aldosterone, and adrenaline. Cortisol is a hormone that helps regulate the metabolism and response to stress, while aldosterone helps regulate blood pressure and electrolyte balance.

Addison's disease is caused by damage to the adrenal glands caused by a variety of factors, including an immune system disorder, cancer, or other underlying illnesses. In some instances, the immune system attacks the adrenal glands by mistake, causing damage and dysfunction. This type of Addison's disease is known as autoimmune-mediated hypoadrenocorticism.

Cancer can also cause Addison's disease by directly damaging the adrenal glands or by spreading to other areas of the body, such as the lymph nodes, and disrupting the normal function of the adrenal glands. Certain underlying diseases, such as amyloidosis, can also induce adrenal gland damage and result in Addison's disease.
Another cause of Addison's disease in dogs is the prolonged use of corticosteroids, which can suppress the adrenal gland's ability to produce hormones. Corticosteroids are often used to treat inflammation and other conditions in dogs, but long-term use can lead to adrenal gland suppression, which can result in Addison's disease.

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